REPRODUCTIVE ORGAN DAMAGE OF DOMESTIC RUMINANTS IN AFRICAN ANIMAL TRYPANOSOMIASIS: A REVIEW

Authors

  • A. A. AJAKAIYE
  • M. A. ABDULLAHI
  • T. O. OLANREWAJU

DOI:

https://doi.org/10.33003/jaat.2021.0702.047

Keywords:

Trypanosomiasis, Pituitary gland, Endocrine, Ruminant, Spermatogenesis, Oestrus cycle

Abstract

Animal African trypanosomiasis affects both production and reproduction in domestic ruminants. The reproductive damages caused by trypanosomes have direct or indirect link to some specific organs like endocrine and pituitary gland which secrets follicle stimulating hormone (FSH), interstitial-cell stimulating hormone (ICSH) and growth hormone (GH). These hormones play an important role in the spermatogenic cycle in males and oestrus cycle in females. However, the pathogenesis of these damages have not been clearly elucidated. We believe that this aspect deserves closer study especially in livestock where reproductive performance is the pillar upon which productivity is built. It is hoped that this review which is centred on the chronological report of works that have been carried out on some reproductive organs damage in domestic ruminants infected with or affected by trypanosomes will add more light to the pathophysiology of the affected organs

References

Abebe, G. R., Eley, R. M. and Kole-Moiyoi, O. (1993). Reduced responsiveness of the hypothalamic-pituitary-gonadal axis in Boran cattle infected with T. congolense. Acta Endocrinology (Copenhangen), 129:74-80

Adamu, S., Fatihu, M. Y., Useh, N. M., Ibrahim, N. D. G., Mamman, S. M., Sekoni, V. O. and Esievo, K. A. N. (2006). Testicular pathological changes in relation to serum concentration of testosterone in Trypanosoma vivax-infected Fulani bulls. Journal of Animal and Veterinary Advance. 5(12): 1165-11

Adamu, S., Fatihu, M. Y., Useh, N. M., Mamman, M., Sekoni, V. O. and Esievo, K. A. N. (2007). Sequential testicular and epididymal damage in Zebu bulls experimentally infected with Trypanosoma vivax. Veterinary Parasitology, 143(1): 29-34

Adenowo, T. K., Njoku, C. O., Oyedipe, E. O. and Sanusi, A. (2005). Lesion of the hypothalamus, adenohypophysis and the ovaries in Trypanosoma vivax infected Yankasa Ewes. Nigerian Veterinary Journal, 26:56–62

Akpavie, S. O., Ikede, B. O. and Egbunike, G. N. (1987). Ejaculate characteristic of sheep infected with Trypanosoma brucei and Trypanosoma vivax: Changes caused by treatment with Diminazene aceturate. Research in Veterinary Science, 42:1-6

Anosa, V. O. (1983). Diseases produced by Trypanosoma vivax in ruminants, horses and rodents. Veterinary Medicine. B 30.111-141

Anosa, V. O. and Isoun, T. T. (1980). Further observation on the testicular pathology in Trypanosoma vivax infection of sheep and goats. Research in Veterinary Science 28:151-160

Apted, P. I. C (1970). Clinical manifestation and diagnosis of sleeping sickness in the African trypanosomiasis, Reviewed by H. W. Mulligan and W. H. Potts. Allen and Unwin, London, UK

Bentivoglio, M., Grassi-Zucconi, G., Olsson, T. and Kristensson, K. (1994). Trypanosoma brucei and the nervous system. Trends in Neuroscience, 17(8): 325-329

Boly, H., Humblot, P., Tillet, Y. and Thibier, M. (1994). Effects of Trypanosoma congolense infection on the pituitary gland of Baoule bulls: Immuno-histochemistry of LH- and FSH-secreting cells and response of plasma LH and testosterone to combined dexamethasone and GnRH treatment. Journal of Reproduction and Fertility, 100:157-162

Clermont, Y. and Morgentaler, H. (1955). Quantitative study of spermatogenesis in the hypophysectomised rat. Endocrinology, 57:369-382

Desquesnes, M. (2004). Livestock trypanosomes and their Vectors in Latin America (English translation). Published by World Organization for Animal Health (OIE), pp: 8-19

Dubey, J. P., Buxton, D. and Wouda, W. (2006). Pathogenesis of bovine neosporosis. Journal of Comparative Pathology, 134:267–289

Farin, P. W., Chenoweth, P. J., Tomky, D. F., Ball, L. and Pexton, J. E. (1989) “Breeding soundness, libido and performance of beef bulls mated to estrus synchronized females”. Theriogenology. 32:717-725.

Faye, D., Sulon, J., Kane, Y., Beckers, J. F., Leak, S., Kaboret, Y., Sousa, N. M., Losson, B. and Geerts, S. (2004). Effects of an experimental Trypanosoma congolense infection on the reproductive performance of West African dwarf goats. Theriogenology, 62:1438-1451

Food and Agricultural Organization (1994). Animal production and Health Papers No 12, Rome, Italy, 1-3

Grundler, G. (1985). The influence of trypanosomiasis on sperm quality. In the Proceedings of the 18th Meeting of the OAU/ISCTR. Harare, Zimbabwe.

Ikede, B. O. (1979). Genital lesions in experimental chronic Trypanosoma brucei infection in rams. Research in Veterinary Sciences, 26: 145-151

Ikede, B. O. and Akpavie, S. O. (1982). Delay in resolution of trypanosome-induced genital lesions in male rabbits infected with Trypanosoma brucei and treated with diminazene aceturate. Research in. Veterinary Science, 32:374-376

Ikede, B. O., Elhassan, E. and Akpavie, S. O. (1988). Reproductive disorders in African trypanosomiasis: A review. Acta Tropica, 45:5-10

Ikede, B. O. and Losos, G. J. (1975). Studies on the pathogenesis of Trypanosoma brucei infection in sheep: Hypophysical and other endocrine lesions. Journal of Comparative Pathology, 85:37-44

Ikede, B. O., Akpokodje, J. U., Hill, D. H. and Ajidagba, P. O. (1977). Clinical haematological and pathological studies in donkeys experimentally infected with Trypanosoma brucei. Tropical Animal Health Production, 9:93-98

Isoun, T. T. and Anosa, V. O. (1974). Lesions in the reproductive organs of sheep and goats infected with T. vivax. Tropenmedizin und Parasitologie, 25:469–476

Isoun, T. T., Akpokodje, J. U. and Anosa, V. O. (1975) Testicular changes in white Fulani zebu (Bunaji) cattle experimentally infected with Trypanosoma vivax: A preliminary report. Journal of Nigerian Veterinary Medical Association, 4:107-108

Kaaya, G. P. and Oduor, O. (1980). The effect of Trypanosoma congolense infection on the testis and epididymis of goat. Bulletin Animal Health Production in Africa, 28:1-5

Khisk, W. H. (2008). Interrelationship between ram plasma testosterone level and some semen characteristics. Slovak Journal of Animal Science, 41:67-71

Leigh, O. O. and O. E. Fayemi, (2013). The effects of experimental Trypanosoma brucei infection on hormonal changes during the oestrous cycle, pregnancy and pregnancy outcome in West African dwarf goat does. Wayamba Journal of Animal Science, 5:685–695

Leigh, O. O., Emikpe, B. O. and Ogunsola, J. O. (2014). Histopathological changes in some reproductive and endocrine organs of Trypanosoma brucei infected West African dwarf goat does. Bulgarian Journal Veterinary Medicine, ISSN 1311-1477; online at http://tru.uni-sz.bg/bjvm/bjvm.htm

Losos, G. J. and Ikede, B. O. (1970). Pathology of experimental trypanosomiasis in the albino rat, rabbit, goat and sheep. A preliminary report. Canada Journal of comparative medicine, 34:209-212

Losos, G. J. and Ikede, B. O. (1972). Review of pathology of disease in domestic and laboratory animals caused by T. congolense. T. vivax, T. rhodesiense and T. gambiense. Veterinary Pathology, 9: 1-71

Marcato, P. S., Benazzi, C., Vecchi, G., Galeotti, M., Salda, D. L., Sarli, G. and Lucidi, P. (1991). Clinical and pathological features of viral haemorrhagic disease of rabbits and the European brown hare syndrome. Revue Scientifique et Technique de l’Office International des Epizooties, 10, 371–392

Masake R. A. (1980). The pathogenesis of infection with Trypanosoma vivax in goats and cattle. Veterinary Research 107:551-557

Maudlin, I. (2006). Centennial review: African trypanosomiasis. Annals of Tropical Medicine and Parasitology, 100:679-701

Morrison, W. I., Murray, M., Sayer, P. D. and Preston J. M. (1981). The pathogenesis of experimentally induced Trypanosoma brucei infection in the dog’s tissue and organ damage. American Journal Pathology, 102:168-181

Moulton, J. E. and Sollod, A. E. (1976). Clinical, serologic and pathologic changes in calves with experimentally induced Trypanosoma brucei infection. American Journal of Veterinary Research. 37. 791- 802.

Mutayoba, B. M., Eckersall, P. D., Jeffcoate, I. A. Cestnik, V. and Holmes, P. H. (1994). Effect of Trypanosoma congolense infection in ram on the pulsative secretion of LH and testosterone and responses to injection of GnRH. Journal of Reproduction and Fertility, 102: 425-431

Nix, J. P., Spitzer, J. C. and Chenoweth, P. J. (1998). Serum testosterone concentration, efficiency of oestrus detection and libido expression in androgenized beef cows. Theriogenology. 49: 1195-1207

Nyeko, J. H. P., Ole-MoiYoi, O. K., Majiwa, P. A. O., Otieno, L. H. and Ociba, P. M. (1990). Characterization of trypanosome isolates from cattle in Uganda using species-specific DNA probes reveals predominance of mixed infections. Insect Science Applied, 11:271-280

Office of the International Epizootic (2013). Trypanosomosis-tsetse transmitted. OIE Terrestrial Manual, pp. 1-11.

Okubanjo, O. O., Sekoni, V. O., Ajanusi, O. J. and Adeyeye, A. A. (2014). Semen characteristics and reaction time of Yankasa rams experimentally infected with Trypanosoma congolense. Global Veterinaria 13(3): 297-301

Raheem, K. A., Fayemi, E. O., Leigh, O. O. and Ameen, S. A. (2009). Selected fertility parameters of West African dwarf buck experimentally infected with Trypanosoma congolense. Folia Veterinaria. 53(2): 68-71

Raheem, K. O. (2014). A review of trypanosomosis-induced reproductive dysfunctions in male animals. Agrosearch, 14(1):30-38

Rakha, E, Puls, F, Saidul, I and Furness, P. (2006). Torsion of the testicular appendix: Importance of associated acute inflammation. Journal of Clinical Pathology, 59: 831-834.

Reincke, M., Arlt, W., Heppner, C., Petzke, F., Chrousos, G. P. and Allolio, B. (1998). Neuroendocrine dysfunction in African Trypanosomiasis: The role of cytokines. Annals New York Academic Science, 840:809-821

Rocha, G., Martins, A., Gama, G., Brandao, F. and Atouguia, J. (2004). Possible cases of sexual and congenital transmission of sleeping sickness. The Lancet, 363, 247

Rodriguez M. M., Oliveira, A. V. and Bellio, A. (2012). The immune response to Trypanosoma cruzi: Role of Toll-like receptors and perspectives for vaccine development. Journal of Parasitology Research; doi:10.1155/2012/507874

Samdi, S. M., Abenga, J. N., Attahir, A., Haruna, M. K., Wayo, B. M., Fajinmi, A. O., Sumayin, H. M., Usman, A. O., Hussaina, J. Z., Muhammad, H., Yarnap, J. E., Ovbagbedia, R. P. and Abdullahi, R. A. (2010). Impact of trypanosomosis on food security in Nigeria: A Review International Journal of Animal and Veterinary Advances, 2:47-50

Sekoni, V. O., Njoku, C. O., Kumi-Diaka J. and Saror, D. I. (1990). Pathological changes in male genitalia of cattle infected with Trypanosoma vivax and Trypanosoma congolense. British Veterinary Journal, 146: 175-180

Sekoni, V. O. (1992). Effect of Trypanosoma vivax on semen characteristics of Yankasa rams. British Veterinary Journal, 148:501-506

Sekoni, V. O., Rekwot, P. I. and Bawa, E. K. (2004). Effect of Trypanosoma vivax and Trypanosoma congolense infection on the reaction time and semen characteristic of Zebu (Bunaji) Friesian cross breed bull. Theriogenology. 61 (1): 55-62

Senger, P. L. (2005). Pathways to pregnancy and parturition. Pullman: Current Conceptions Inc. 2nd Eds., pp. 373

Silva, T. M., Olinda, R. G., Rodrigues, C. M., Camara, C. L., Lopes, F. C., Coelho, W. A. (2013). Pathogenesis of reproductive failure induced by Trypanosoma vivax in experimentally infected pregnant ewes. Veterinary Research, 44: 1-6.

Steinberger, E. and Duckett, G. E. (1967). Hormonal control of spermatogenesis. Journal of Reproductive Fertility, 2:75-87

Victor, I., Sackey, A. K. B. and Natala, A. J. (2012). Penile protrusion with haemorrhages and prepucial inflammation in pigs experimentally infected with Trypanosoma congolense. Journal of Animal Production Advances, 2(6): 297-302

Waindi, E. N., Gombe, S. and Oduor–Okelo, D. (1986). Plasma testosterone in Trypanosoma congolense infected Togara goats. Archives of Andrology, 17:9-17

Wellde, B. T., Reardon, M. I, Chumo, D. A., Kovatch, R. M., Wacma, D., Wykoff, D. E, Mwangi, J., Boyce, W. L and Williams, J. S. (1989). Cerebral trypanosomiasis in naturally-infected cattle in Larnbwe Valley, South Nyanza, Kenya. Annals of Tropical Medicine and Parasitology, 83:151-160

Downloads

Published

2022-06-06